Commercial Strategy and Execution for Life Sciences

From Science to Patients

Decode is a global life science advisory firm. Since 2012 we have helped biotech, biopharma and medtech companies bring needed therapies to market and build corporate value

Who we work with

Our core focus
Emerging biotech and biopharma
Building the commercial organization and preparing a first launch, from early clinical strategy to launch readiness.
Commercial-stage
Established commercial companies
Brand growth, relaunch, indication expansion, portfolio strategy and lifecycle management.
Investors and partners
Boards, investors and BD teams
Asset diligence, opportunity valuation, partnering and capital strategy.

Services

Depth in every commercial function

One partner across the commercial organization, from a first launch to an established portfolio. Every program is sized to the asset, the stage and the company

01
Marketing
Go-to-market strategy and functional plans
Positioning and core message platform
Trade name, branding and agency selection
Advocacy and disease awareness
02
Sales
Sales force size, structure and deployment
Build vs. rent guidance at board level
Targeting, alignments and incentives
Specialty and rare disease field design
03
Value, Access & Reimbursement
Pricing and payer strategy
Value proposition and budget impact model
Patient support and hub development
Contracting and government price reporting
04
Commercial Operations & CI
AI-assisted forecasting and P&L
Market research and data acquisition
AI-enabled CI and congress monitoring
Launch readiness planning and PMO
05
Channel & CMC
Distribution and specialty pharmacy strategy
3PL selection and implementation
Order-to-cash operations
Packaging and serialization integration

Sized to every stage

Commercial input belongs alongside drug development, not exclusively during Phase 3. We time each workstream to the business decisions that shape an asset’s value, from indication selection and trial design to formulation, dosing and label.

Pre-Clinical
Discovery
Informs: indication selection, asset prioritization
Disease area prioritization
Unmet need and competitive landscape
Opportunity valuation
Early Stage Clinical
Phase 1/2
Informs: trial design, formulation, dosing
Target product profile, tested
Commercial input on trial design
Draft label and trade name
Late Stage Clinical & Launch Readiness
Phase 3 · NDA/BLA
Informs: label, pricing, launch sequence
L-24 strategy critical path
L-12 execution critical path
Launch readiness dashboard
Commercial Stage & LCM
Phase 4 · LOE
Informs: new indications, LCM, partnering
Brand performance diagnostics
Lifecycle and LOE planning
Partnerships and global expansion

Enterprise transformation

From R&D organization to commercial-stage company, with commercial strategy integrated into every corporate function.

Commercial strategy
Connected to 8 corporate functions
Finance & Administration
Budgeting, P&L and forecasts
Capital strategy and IR
GTN and government reporting
HR & Corporate Communications
Organization design and culture
Recruiting, staffing, training
PR and internal communications
IT, Data & Systems
ERP and commercial software
Data infrastructure and BI
Serialization integration
Medical Affairs
KOL networks and MSL strategy
Medical messaging and positioning
Publications and congresses
Legal, Regulatory & Compliance
State licensing
Compliance build and SOPs
Vendor contracts, data privacy
CMC & Supply Chain
Commercial supply and S&OP
CMO and 3PL management
Forecast and safety stock
BD, Licensing & Partnerships
Partnership and licensing strategy
Alliance management
Global expansion
R&D and Clinical
LCM and asset strategy
Commercial input on trial design
Label optimization

Approach

An extension of your team

We advise boards and leadership teams, build the commercial strategy and execute it, staffing critical roles until your organization is in place. Engage us for one capability or all three.

01

Insights-Based Advisory

Evidence from customers, markets and competitors, translated into clear commercial decisions. AI-enabled research synthesis compresses weeks of work into days.

Market and landscape assessment
HCP, payer and patient research
AI-enabled CI and congress monitoring
Board and C-suite advisory
02

Strategy Development

A disease-appropriate commercial strategy, right-sized to the company, with a critical path built back from launch.

Go-to-market model and launch plan
AI-assisted forecasting, P&L and valuation
Pricing, value and access strategy
Organization design, build vs. rent
03

Full-Time & Fractional Operational Excellence

Senior operators who execute the plan, in full-time or fractional roles, until your team is built.

Fractional CCO and functional leads
Launch readiness PMO and dashboards
Vendor selection: 3PL, hub, AOR
Hiring, onboarding and handover

Experience

Deep experience acrosss therapeutic areas and modalities

Specialists in first launches, with equal depth in established brands, relaunches and lifecycle programs, at large pharma and emerging biotech.

25+Product launches
37+Products supported
50%Of launches were a company’s first product
US + ex-USUS and global launch experience

Disease Areas

Launch, lifecycle and clinical-stage programs, by indication.

Oncology & Hematology
Hematologic
DLBCL, FL, NHL, Burkitt’s lymphoma
AML, ALL, CLL
Multiple myeloma
PNH, sickle cell disease
Solid tumors
Melanoma, NSCLC, head and neck
Platinum-resistant ovarian, ccRCC
Pancreatic adenocarcinoma, mCRC
Breast cancer: HR+/HER2–, HER2+
Bladder (NMIBC), pediatric low-grade glioma
Cardiometabolic & Renal
Hypercholesterolemia
AF, HCM, heart failure
IST / POTS
Primary IgA nephropathy
Hyperuricemia
Neurology & CNS
Migraine
Parkinson’s disease
Tardive dyskinesia
Narcolepsy
MDD and treatment-resistant depression
Generalized anxiety disorder and anxious depression
Eating disorders
Endocrinology, Bone & Musculoskeletal
Osteoporosis
Osteoarthritis: knee, hip
Pain: peri- and post-surgical
Immunology & Inflammation
Rheumatoid arthritis
PsA, AS, plaque psoriasis
Severe asthma
Rare & Specialty
Epidermolysis bullosa
Cystic fibrosis
Envenomation, anaphylaxis
Wound management
Women’s Health
Endometriosis
Uterine fibroids
Ophthalmology
Neovascular AMD
Cataracts and age-related crystallin disorders

Modalities

Commercial models shaped by the science, from high-COGS cell and gene therapies to small molecules and devices.

01
Cell & Gene Therapy
Pricing, GTN and supply chain for high-COGS, ex-US manufactured therapies.
Cell and gene therapies
CAR-T and CAR-NK
02
Antibodies & Conjugates
First-in-class and first-product launches in oncology and specialty care.
Monoclonal antibodies
Bispecifics
Antibody-drug conjugates
03
Biologics & Viral
Novel mechanisms that require market shaping and education.
Biologics and peptides
Oncolytic viruses
Antivenoms and antidotes
04
Small Molecules & Devices
Competitive specialty and primary care markets, including fixed-dose combinations.
Small molecules
Combination therapies
Novel drug delivery
Medical devices and OTC

Team

Senior leadership for every engagement

Carolina Petrini

Managing Partner, Chief Commercial Officer (full & fractional)

–    Carolina is a commercial executive and board member with 26 years across biopharma, biotech and medtech. She has led commercial strategy, four specialty launches, each meeting or exceeding its launch KPIs, and contributed to more than 37 launch, relaunch and readiness programs, including BioPharma Dive’s Drug Launch of the Year.

–    Her work starts long before launch: indication selection and sequencing, target product profiles, pricing corridors and payer-validated forecasts used directly in Board and investment decisions. She designs and builds commercial organizations from a blank page, go-to-market strategy, and has held P&L responsibility of $80M to $150M.

–    Carolina has worked as a full-time, fractional and interim CCO in emerging biotech and inside large, matrixed organizations, alongside headquarters in Europe, Asia and Latin America.

Board and investor work

–    Carolina is a commercial executive and board member with 26 years across biopharma, biotech and medtech. She has led commercial strategy, four specialty launches, each meeting or exceeding its launch KPIs, and contributed to more than 37 launch, relaunch and readiness programs, including BioPharma Dive’s Drug Launch of the Year.

–    Her work starts long before launch: indication selection and sequencing, target product profiles, pricing corridors and payer-validated forecasts used directly in Board and investment decisions. She designs and builds commercial organizations from a blank page, go-to-market strategy, and has held P&L responsibility of $80M to $150M.

–    Carolina has worked as a full-time, fractional and interim CCO in emerging biotech and inside large, matrixed organizations, alongside headquarters in Europe, Asia and Latin America.

The Decode Network

Expertise curated for each engagement

Former commercial leaders from large pharma and emerging biotech, with deep disease area expertise. We assemble the experts each asset, stage and company requires.

Contact

Carolina Petrini, Managing Partner